If you want to task between the two, I recommend either a USB headset, or using the Front Panel to override your speakers when you want just headphones so you don't have to climb behind your case. Really? But Asus's website says that it supports jack-retasking and I have seen it been done on other fourms with an Asus Realtek manager. I finally figured it out after 2 hours, same issue as nitsua101. I have asus cm1855 w/ windows 10 & realtek audio manager. I wanted to be able to switch between using speakers or headphones using only realtek audio vs physically switching ports/jacks.
I ended having to plug headphones into the headphone jack in front of computer, and the speakers into the back to the light green lower center jack (front speaker out).